I used one with Fedora for a while. The problem I had is whenever it would randomly disconnect, Fedora could not handle it gracefully. It would lock up the system and require a hard reboot. Windows has been a bit more graceful about things. I’m hoping the next generation or maybe oculink will be better.
Another thing to note, it seems that immutable is the future of linux. The Fedora project roadmaps the Atomic desktop taking over the traditional Workstation. OpenSUSE also looks to be moving to it as the default in Leap 16. Being new to the ecosystem might be advantageous because you don’t have the old habits.